Artemisia annua (Sweet Annie), Other Artemisia Species, Artemisinin, Artemisinin Derivatives, and Malaria
نویسندگان
چکیده
منابع مشابه
Artemisia annua (Sweet Annie), Other Artemisia Species, Artemisinin, Artemisinin Derivatives, and Malaria
This paper reviews the use of whole-plant Artemisia annua (sweet Annie) as it pertains to malaria including history, chemistry, clinical efficacy, pharmacokinetics, dosing, safety, and resistance. Artemisinin, the sesquiterpene lactone found in the plant, and various semi-synthetic variants of it used as critical drugs around the world for malaria are discussed in comparison to the whole plant....
متن کاملExamining The Extraction Of Artemisinin From Artemisia Annua Using Ultrasound
Artemisinin suppresses the life-cycle of the plasmodium parasite which causes malaria. It is found naturally occurring within the trichome glands of the Artemisia annua plant. Traditional methods for extracting artemisinin are time-consuming and have high environmental impact due to the temperatures and organic solvents which must be employed. Ultrasound decreases these through acoustic streami...
متن کاملDried whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin.
Pharmaceutical monotherapies against human malaria have proven effective, although ephemeral, owing to the inevitable evolution of resistant parasites. Resistance to two or more drugs delivered in combination will evolve more slowly; hence combination therapies have become the preferred norm in the fight against malaria. At the forefront of these efforts has been the promotion of Artemisinin Co...
متن کاملAn Endophytic Pseudonocardia Species Induces the Production of Artemisinin in Artemisia annua
Endophytic actinobacteria colonize internal tissues of their host plants and are considered as a rich and reliable source of diverse species and functional microorganisms. In this study, endophytic actinobacterial strain YIM 63111 was isolated from surface-sterilized tissue of the medicinal plant Artemisia annua. We identified strain YIM 63111 as a member of the genus Pseudonocardia. A. annua s...
متن کاملArtemisia Annua (qinghao): a Pharmacological Review
Artemisia annua L., also known as sweet wormwood, sweet annie, sweet sagewort and annual wormwood (Chinese: qngho), is a common type of wormwood that is native to temperate Asia, but naturalized throughout the world, and that belongs to the family of the Asteraceae. Currently, Artemisia annua is the source for the production of artemisinin and semi-synthetic artemisinin derivatives (including d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Restorative Medicine
سال: 2014
ISSN: 2165-7971
DOI: 10.14200/jrm.2014.3.0105